| # | Player | G | Passing Yards |
|---|---|---|---|
| 1 | Aaron Rodgers PIT | 4 | 999 |
| 2 | Bryce Young CAR | 3 | 939 |
| 3 | Tyler Shough NO | 3 | 917 |
| 4 | Matthew Stafford LAR | 3 | 872 |
| 5 | Deshaun Watson CLE | 4 | 855 |
| 6 | Jordan Love GB | 3 | 844 |
| 7 | Patrick Mahomes KC | 3 | 812 |
| 8 | Jared Goff DET | 3 | 802 |
| 9 | C.J. Stroud HOU | 3 | 794 |
| 10 | Brock Purdy SF | 3 | 789 |
| 11 | Josh Allen BUF | 3 | 786 |
| 12 | Geno Smith NYJ | 3 | 783 |
| 13 | Lamar Jackson BAL | 3 | 745 |
| 14 | Joe Burrow CIN | 3 | 743 |
| 15 | Dak Prescott DAL | 3 | 730 |
| 16 | Kirk Cousins LV | 3 | 661 |
| 17 | Jacoby Brissett ARI | 3 | 652 |
| 18 | Justin Herbert LAC | 3 | 627 |
| – | Malik Willis MIA | 3 | 627 |
| 20 | Jalen Hurts PHI | 3 | 620 |
| 21 | Trevor Lawrence JAX | 3 | 616 |
| 22 | Baker Mayfield TB | 3 | 615 |
| 23 | Daniel Jones IND | 3 | 611 |
| 24 | Bo Nix DEN | 3 | 605 |
| 25 | Drake Maye NE | 3 | 585 |
| 26 | Cam Ward TEN | 3 | 504 |
| 27 | Drew Lock SEA | 2 | 422 |
| 28 | Caleb Williams CHI | 2 | 407 |
| 29 | Sam Darnold SEA | 2 | 392 |
| 30 | Marcus Mariota WSH | 2 | 294 |
| 31 | Carson Wentz MIN | 2 | 276 |
| 32 | Jayden Daniels WSH | 2 | 260 |
| 33 | Michael Penix Jr. ATL | 1 | 256 |
| 34 | Jaxson Dart NYG | 2 | 250 |
| 35 | Case Keenum CHI | 1 | 247 |
| 36 | Cooper Rush ATL | 2 | 229 |
| – | Jameis Winston NYG | 2 | 229 |
| 38 | Kyler Murray MIN | 2 | 186 |
| 39 | Jack Strand ATL | 1 | 59 |
| 40 | Tyson Bagent CHI | 1 | 54 |
| 41 | Tommy DeVito NE | 1 | 30 |
| 42 | Efton Chism III NE | 2 | 16 |
| 43 | Jaxon Smith-Njigba SEA | 3 | 14 |
| 44 | Stetson Bennett IV LAR | 1 | 13 |