| # | Player | G | Passing Yards |
|---|---|---|---|
| 1 | Jared Goff DET | 18 | 4,942 |
| 2 | Joe Burrow CIN | 17 | 4,918 |
| 3 | Baker Mayfield TB | 18 | 4,685 |
| 4 | Patrick Mahomes KC | 19 | 4,607 |
| 5 | Lamar Jackson BAL | 19 | 4,601 |
| 6 | Sam Darnold MIN | 18 | 4,564 |
| 7 | Jayden Daniels WSH | 20 | 4,390 |
| 8 | Josh Allen BUF | 19 | 4,367 |
| 9 | Geno Smith SEA | 17 | 4,320 |
| 10 | Matthew Stafford LAR | 18 | 4,295 |
| 11 | C.J. Stroud HOU | 19 | 4,254 |
| 12 | Justin Herbert LAC | 18 | 4,112 |
| 13 | Bo Nix DEN | 18 | 3,919 |
| 14 | Aaron Rodgers NYJ | 17 | 3,897 |
| 15 | Brock Purdy SF | 15 | 3,864 |
| 16 | Kyler Murray ARI | 17 | 3,851 |
| 17 | Jalen Hurts PHI | 19 | 3,629 |
| 18 | Jordan Love GB | 16 | 3,601 |
| 19 | Caleb Williams CHI | 17 | 3,541 |
| 20 | Kirk Cousins ATL | 14 | 3,508 |
| 21 | Tua Tagovailoa MIA | 11 | 2,867 |
| 22 | Russell Wilson PIT | 12 | 2,752 |
| 23 | Bryce Young CAR | 14 | 2,403 |
| 24 | Drake Maye NE | 13 | 2,276 |
| 25 | Derek Carr NO | 10 | 2,145 |
| 26 | Jameis Winston CLE | 11 | 2,121 |
| 27 | Will Levis TEN | 12 | 2,091 |
| 28 | Daniel Jones NYG | 10 | 2,070 |
| 29 | Trevor Lawrence JAX | 10 | 2,045 |
| 30 | Gardner Minshew LV | 10 | 2,013 |
| 31 | Dak Prescott DAL | 8 | 1,978 |
| 32 | Cooper Rush DAL | 12 | 1,844 |
| 33 | Anthony Richardson IND | 11 | 1,814 |
| 34 | Joe Flacco IND | 7 | 1,761 |
| 35 | Mac Jones JAX | 10 | 1,672 |
| 36 | Aidan O'Connell LV | 9 | 1,612 |
| 37 | Mason Rudolph TEN | 8 | 1,530 |
| 38 | Spencer Rattler NO | 7 | 1,317 |
| 39 | Deshaun Watson CLE | 7 | 1,148 |
| 40 | Justin Fields PIT | 11 | 1,106 |
| 41 | Drew Lock NYG | 7 | 1,071 |
| 42 | Andy Dalton CAR | 6 | 989 |
| 43 | Tyler Huntley MIA | 5 | 829 |
| 44 | Jacoby Brissett NE | 7 | 826 |
| 45 | Michael Penix Jr. ATL | 5 | 775 |
| 46 | Malik Willis GB | 6 | 550 |
| 47 | Desmond Ridder LV | 5 | 458 |
| 48 | Dorian Thompson-Robinson CLE | 6 | 440 |
| 49 | Marcus Mariota WSH | 5 | 364 |
| 50 | Joshua Dobbs SF | 2 | 361 |
| 51 | Jimmy Garoppolo LAR | 1 | 334 |
| 52 | Tanner McKee PHI | 2 | 323 |
| 53 | Kenny Pickett PHI | 7 | 291 |
| 54 | Trey Lance DAL | 4 | 266 |
| 55 | Tommy DeVito NYG | 2 | 257 |
| 56 | Joe Milton III NE | 1 | 241 |
| 57 | Jake Haener NO | 8 | 226 |
| 58 | Davis Mills HOU | 4 | 212 |
| 59 | Brandon Allen SF | 3 | 199 |
| 60 | Skylar Thompson MIA | 2 | 187 |
| 61 | Mitchell Trubisky BUF | 9 | 179 |
| 62 | Bailey Zappe CLE | 1 | 170 |
| 63 | Tim Boyle MIA | 2 | 153 |
| 64 | Tim Boyle NYG | 1 | 123 |
| 65 | Tyrod Taylor NYJ | 2 | 119 |
| 66 | Carson Wentz KC | 2 | 118 |
| 67 | Hendon Hooker DET | 3 | 62 |
| 68 | Nick Mullens MIN | 4 | 38 |
| 69 | Jaxon Smith-Njigba SEA | 17 | 35 |
| 70 | AJ Cole LV | 1 | 34 |
| 71 | Courtland Sutton DEN | 17 | 30 |
| 72 | Taylor Heinicke LAC | 4 | 28 |
| – | Mike White BUF | 1 | 28 |
| 74 | Sam Howell SEA | 1 | 24 |
| – | Adonai Mitchell IND | 14 | 24 |
| 76 | David Montgomery DET | 15 | 23 |
| – | Tress Way WSH | 1 | 23 |
| 78 | Justin Jefferson MIN | 18 | 22 |
| 79 | Taysom Hill NO | 8 | 21 |
| – | Cedrick Wilson Jr. NO | 13 | 21 |
| 81 | Jalen Coker CAR | 10 | 19 |
| – | Kyle Allen PIT | 1 | 19 |
| 83 | Riley Dixon DEN | 5 | 18 |
| 84 | Josh Johnson BAL | 4 | 17 |
| – | Jack Fox DET | 1 | 17 |
| 86 | Stefon Diggs HOU | 8 | 13 |
| 87 | Tyson Bagent CHI | 4 | 11 |
| 88 | Clayton Tune ARI | 5 | 8 |
| 89 | Amon-Ra St. Brown DET | 18 | 7 |
| 90 | Kyle Trask TB | 3 | 5 |
| 91 | Bryan Anger DAL | 3 | 4 |
| 92 | JK Scott LAC | 2 | 3 |
| – | Teddy Bridgewater DET | 1 | 3 |