| # | Player | G | Passing TDs |
|---|---|---|---|
| 1 | Matthew Stafford LAR | 20 | 52 |
| 2 | Drake Maye NE | 21 | 37 |
| 3 | Jared Goff DET | 17 | 34 |
| 4 | Trevor Lawrence JAX | 18 | 32 |
| 5 | Caleb Williams CHI | 19 | 31 |
| 6 | Dak Prescott DAL | 17 | 30 |
| – | Sam Darnold SEA | 20 | 30 |
| 8 | Josh Allen BUF | 18 | 29 |
| 9 | Bo Nix DEN | 18 | 28 |
| 10 | Jordan Love GB | 16 | 27 |
| 11 | Justin Herbert LAC | 17 | 26 |
| – | Baker Mayfield TB | 17 | 26 |
| – | Jalen Hurts PHI | 17 | 26 |
| 14 | Bryce Young CAR | 17 | 24 |
| – | Aaron Rodgers PIT | 17 | 24 |
| 16 | Jacoby Brissett ARI | 14 | 23 |
| 17 | Brock Purdy SF | 11 | 22 |
| – | Patrick Mahomes KC | 14 | 22 |
| 19 | C.J. Stroud HOU | 16 | 21 |
| – | Lamar Jackson BAL | 13 | 21 |
| 21 | Tua Tagovailoa MIA | 14 | 20 |
| 22 | Daniel Jones IND | 13 | 19 |
| – | Geno Smith LV | 15 | 19 |
| 24 | Joe Burrow CIN | 8 | 17 |
| 25 | Cam Ward TEN | 17 | 15 |
| – | Jaxson Dart NYG | 14 | 15 |
| 27 | Mac Jones SF | 12 | 13 |
| – | Joe Flacco CIN | 9 | 13 |
| 29 | J.J. McCarthy MIN | 10 | 11 |
| 30 | Tyler Shough NO | 11 | 10 |
| – | Kirk Cousins ATL | 10 | 10 |
| – | Marcus Mariota WSH | 10 | 10 |
| 33 | Michael Penix Jr. ATL | 9 | 9 |
| 34 | Jayden Daniels WSH | 7 | 8 |
| – | Spencer Rattler NO | 9 | 8 |
| 36 | Justin Fields NYJ | 9 | 7 |
| – | Shedeur Sanders CLE | 8 | 7 |
| – | Dillon Gabriel CLE | 10 | 7 |
| 39 | Kyler Murray ARI | 5 | 6 |
| – | Carson Wentz MIN | 5 | 6 |
| – | Jake Browning CIN | 5 | 6 |
| 42 | Tyrod Taylor NYJ | 6 | 5 |
| – | Davis Mills HOU | 6 | 5 |
| 44 | Philip Rivers IND | 3 | 4 |
| – | Mitchell Trubisky BUF | 4 | 4 |
| 46 | Russell Wilson NYG | 6 | 3 |
| – | Quinn Ewers MIA | 4 | 3 |
| – | Malik Willis GB | 4 | 3 |
| 49 | Joe Flacco CLE | 4 | 2 |
| – | Riley Leonard IND | 5 | 2 |
| – | Jameis Winston NYG | 3 | 2 |
| – | Brady Cook NYJ | 5 | 2 |
| – | Tyler Huntley BAL | 5 | 2 |
| – | Mason Rudolph PIT | 6 | 2 |
| 55 | Jarrett Stidham DEN | 2 | 1 |
| – | DJ Moore CHI | 19 | 1 |
| – | Breece Hall NYJ | 16 | 1 |
| – | David Montgomery DET | 17 | 1 |
| – | Andy Dalton CAR | 4 | 1 |
| – | Joe Milton III DAL | 4 | 1 |
| – | Cam Akers MIN | 2 | 1 |
| – | Jauan Jennings SF | 17 | 1 |
| – | Chris Oladokun KC | 3 | 1 |
| – | Gunner Olszewski NYG | 16 | 1 |
| – | Taysom Hill NO | 13 | 1 |
| – | Kenny Pickett LV | 6 | 1 |
| – | Tanner McKee PHI | 4 | 1 |
| – | Josh Johnson WSH | 3 | 1 |