| # | Player | G | Passing Yards |
|---|---|---|---|
| 1 | Jordan Love GB | 9 | 2,618 |
| 2 | Joe Burrow CIN | 8 | 2,386 |
| 3 | Dak Prescott DAL | 9 | 2,381 |
| 4 | Matthew Stafford LAR | 9 | 2,374 |
| 5 | Kirk Cousins LV | 9 | 2,340 |
| 6 | Drake Maye NE | 9 | 2,282 |
| 7 | C.J. Stroud HOU | 8 | 2,251 |
| 8 | Bryce Young CAR | 8 | 2,197 |
| 9 | Jared Goff DET | 8 | 2,134 |
| 10 | Geno Smith NYJ | 9 | 2,078 |
| 11 | Patrick Mahomes KC | 8 | 2,037 |
| 12 | Josh Allen BUF | 8 | 2,027 |
| 13 | Tyler Shough NOP | 8 | 1,986 |
| 14 | Brock Purdy SF | 8 | 1,980 |
| 15 | Trevor Lawrence JAC | 8 | 1,932 |
| 16 | Aaron Rodgers PIT | 8 | 1,871 |
| 17 | Deshaun Watson CLE | 8 | 1,806 |
| 18 | Bo Nix DEN | 9 | 1,730 |
| 19 | Daniel Jones IND | 9 | 1,722 |
| 20 | Jacoby Brissett ARI | 8 | 1,719 |
| 21 | Justin Herbert LAC | 8 | 1,591 |
| 22 | Caleb Williams CHI | 6 | 1,546 |
| 23 | Jayden Daniels WSH | 7 | 1,499 |
| 24 | Cam Ward TEN | 8 | 1,483 |
| 25 | Sam Darnold SEA | 7 | 1,478 |
| 26 | Michael Penix Jr. ATL | 7 | 1,444 |
| 27 | Malik Willis MIA | 8 | 1,396 |
| 28 | Jameis Winston NYG | 8 | 1,028 |
| 29 | Kyler Murray MIN | 6 | 1,022 |
| 30 | Lamar Jackson BAL | 5 | 967 |
| 31 | Jalen Hurts PHI | 5 | 933 |
| 32 | Baker Mayfield TB | 6 | 922 |
| 33 | J.J. McCarthy NYG | 5 | 915 |
| 34 | Tyler Huntley BAL | 5 | 727 |
| 35 | Tanner McKee PHI | 3 | 638 |
| 36 | Drew Lock SEA | 3 | 597 |
| 37 | Jalon Daniels TB | 5 | 501 |
| 38 | Tyson Bagent CHI | 3 | 409 |
| 39 | Carson Wentz MIN | 3 | 357 |
| 40 | Case Keenum CHI | 3 | 355 |
| 41 | Gardner Minshew II ARI | 2 | 354 |
| 42 | Marcus Mariota WSH | 3 | 340 |
| 43 | Shedeur Sanders CLE | 3 | 299 |
| 44 | Jaxson Dart NYG | 2 | 250 |
| 45 | Cooper Rush ATL | 2 | 229 |
| 46 | Athan Kaliakmanis WSH | 1 | 186 |
| 47 | Joe Milton PHI | 1 | 169 |
| 48 | Joe Fagnano BAL | 2 | 151 |
| 49 | Jack Strand ATL | 1 | 59 |
| 50 | Max Brosmer MIN | 1 | 58 |
| 51 | Tommy DeVito NE | 2 | 51 |
| 52 | Fernando Mendoza LV | 1 | 48 |
| 53 | Kenny Pickett CAR | 3 | 47 |
| 54 | Bradley Pinion MIA | 2 | 46 |
| 55 | Tua Tagovailoa ATL | 1 | 34 |
| 56 | DJ Uiagalelei LAC | 1 | 24 |
| 57 | Efton Chism III NE | 8 | 16 |
| 58 | Jaxon Smith-Njigba SEA | 9 | 14 |
| 59 | AJ Cole LV | 1 | 13 |
| – | Stetson Bennett IV LAR | 1 | 13 |
| 61 | Jack Fox DET | 1 | 11 |
| 62 | Anthony Richardson Sr. IND | 1 | 8 |
| – | Quinn Ewers JAC | 2 | 8 |
| 64 | Davis Mills HOU | 1 | 7 |
| – | Michael Wilson ARI | 9 | 7 |